President Donald Trump has signed an executive order to launch the Genesis Mission, a sweeping federal initiative led by the U.S. Department of Energy. The goal: to centralize decades of scientific data from national labs, universities, and private-sector partners into a unified AI platform. This infrastructure will support the training of foundational AI models, the use of AI agents, and the automation of scientific experiments.
The mission aims to dramatically accelerate discovery by making U.S. supercomputers, quantum systems, and advanced scientific instruments work together in a “closed-loop” system. Through predictive models and AI-driven simulations, researchers hope to tackle pressing challenges like nuclear fusion, grid modernization, and materials science — all while shortening research timelines “from years to days or even hours.”
A key part of the strategy is the American Science and Security Platform, which will serve as the backbone for this initiative. It will link high-performance computing resources with sensitive, categorized data: some datasets will be openly available, while others will remain proprietary or security-classified. Trump’s administration sees this as a major step in scientific mobilization, comparing it in ambition to the Apollo Program.
The Genesis Mission also invites public-private collaboration: major tech players are expected to partner with national labs. By uniting government data, world-class AI systems, and cutting-edge computing, the initiative aims to double R&D productivity and drive breakthroughs in energy, medicine, engineering, and national security.
